Ciprofloxacin and Tetracycline Resistance Cause Collateral Sensitivity to Aminoglycosides in Salmonella Typhimurium
نویسندگان
چکیده
The objective of this study was to evaluate collateral sensitivity and cross-resistance antibiotic-induced resistant Salmonella Typhimurium various antibiotics. S. ATCC 19585 (STWT) exposed ciprofloxacin, gentamicin, kanamycin, tetracycline induce antibiotic resistance, respectively, assigned as STCIP, STGEN, STKAN, STTET. susceptibilities the mutants cefotaxime, chloramphenicol, polymyxin B, streptomycin, tetracycline, tobramycin were determined in absence presence CCCP PAβN. STCIP showed gentamicin (1/2 fold) kanamycin (1/4 fold). STTET also cross-resistant ciprofloxacin (128-fold) sensitive (1/4-fold) (1/8-fold). associated with AcrAB-TolC efflux pump outer membrane porin proteins (OmpC). This provides new insight into phenomenon, which can be used for designing effective treatment regimens control antibiotic-resistant bacteria.
منابع مشابه
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ژورنال
عنوان ژورنال: Antibiotics
سال: 2023
ISSN: ['2079-6382']
DOI: https://doi.org/10.3390/antibiotics12081335